Methyl​enedioxy​methamphetamine

For learning/research purposes only!
tmax: 1.9 ± 0.4
Clearance rate: 0.48 ± 0.13 L/kg
Volume of distribution: 4.9 ± 2.6 L/kg
Half-life: 7 hours
Absorption half-life: 0.45 hours

MDA half-life (metabolite): 10.5 hours

HMMA half-life (metabolite): 11.5 hours

Toxic dose on serotonin receptors: 10-40 mg/kg

(most common dosages are 1 mg/kg)

Increases plasma oxytocin to 83.7 pg/ml at 1.5 mg/kg (baseline = 15 pg/ml [500% above baseline])
Increases dopamine by 500% at 7.5 mg/kg, 235% for 3 mg/kg & 1.5 mg/kg failed to alter synaptic DA
Increases serotonin by 3,000% at 7.5 mg/kg & 500% at 1.5 mg/kg & 911% at 3 mg/kg
Full recovery from single dose of 15 mg/kg can take 7 to 21 days (20-40% reduction in 5-HTT-IR)
Full recovery in sleep at 15 mg/kg (single dose) takes 180 days
1.5 mg/kg increases loving and friendly
0.75 mg/kg increases loneliness

Some source!

Update, more source! 

Metabolite half-lives source 

20 mg/kg serotonin toxicity source 

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