Fentanyl

Half-life: 1.98 hours

Volume of distribution: 3.6 L/kg

Clearance rate: 1.26 L/kg/h

Tmax: 39.7 ± 17.4 minutes

Absorption half-life: 10 minutes

LD50: 1 mg/kg

LDLo: 0.028 mg/kg

Dose for analgesia: 1 ng/ml (0.0036 mg/kg) and 2 ng/ml

Dose for anesthesia is 10 ng/ml (0.036 mg/kg) and 20 ng/ml

Increases b-endorphins by 30-fold

Is 50-fold more potent than heroin

Is 100-fold more potent than Morphine

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