Half-life 6.6 hours
Clearance rate: 0.065 L/kg/h ± 0.02 L/kg/h
Volume of distribution: 0.62 L/kg ± 0.13 L/kg
Tmax: 2 hours (10 hours for dogs)
Absorption half-life: 0.5 hours (3.5 hours for dogs)
LD50: 1,000 mg/kg (300 mg/kg for dogs, 200 mg/kg for cats, 950 mg/kg rats)
Toxic dose (dogs): 100 mg/kg
10-fold less potent than caffeine (methyltheobromine)
Theobromine concentration in milk chocolate 1 g/kg (1 mg/g)
Theobromine concentration in dark chocolate 10 g/kg (10 mg/g)