Oral half-life: 24.4 hours (30 minutes at concentrations ≥70uM [calculated to 2.34 mg/kg]) source source
Absorption half-life: 0.78 hours
Tmax: 2.1 hours source
Estimated tmax with high concentration dose: 0.89 hours
Volume of distribution: 0.19 mg/kg/L source
Bioavailability: 50%–90% (dose-dependant) source
Baseline plasma concentration is 65 umol/mL (calculated to 2.18 mg/kg [2.42 mg/kg adjusted for bioavailability]) source
Maximum concentration via oral administration: 220 micromol/L (calculated to 7.36 mg/kg)
Maximum concentration via IV administration: 26,000 micromol/L
Decreases urinary pH by 0.58 source
Renal threshold (excess is excreted unchanged): 1.4 mg/100 mL (calculated to 2.66 mg/kg) source
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