GABA

Dosage for calming effects: 1.4 mg/kg
Dosage for sleep: 100 mg/kg (sleep frequency decrease 20.7%, increase sleep duration 87.3%)
Doses at 150-300 mg are shown to improve sleep

GABA taken at doses of 5 mg/kg increase GABA to 200%-300% above baseline
Increases GABA 33% above baseline in the brain
Increases GABA 383.3% above baseline combined with l-arginine
LD50 is 12,680 mg/kg
NOAEL 500 mg/kg
LDLO 2,400 mg/kg

The half-life 5.28 hours (17 minutes in mice)
Tmax: 1.5 hours (0.75 - 2)

Bulk density: 0.36 g/mL ref
Clearance rate 2090.38 L/h ± 85.17% (34.16 L/kg)
Volume of distribution 15924.6 L ± 116.84% (260.2 L/kg)
absorption half-life: 0.36 hours
3 g (34 mg/kg) increases H.G.H. by 400% above baseline
5 g increases H.G.H. by 550% above baseline
Baseline GABA levels 0.01 mg/L

Nitric Oxide helps gaba pass blood brain barrier; L-arginine increases nitric oxide