Toxic dose 30 mg/kg
LDLO 203.3±3.3 mg/kg
LD50 226.7±4.4 mg/kg
LD100 258.3±8.8 mg/kg
Half-life 6.9 minutes
Volume of distribution 1858 ml
Clearance rate 186 ml/min
AUC 35.9 ug/ml-min
Absorption half-life 16.72 minutes
12.5 mg/kg - 25 mg/kg significantly increase Dopamine in the nucleus accumbens shell
50 mg/kg significantly increases Dopamine in nucleus accumbens shell
Estimated minimum detection level 0.024 mg/kg (own data)
Bioavailability 100%
source
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