Rhodiola

Half-life 0.93 hours
Clearance rate 1.5 L/h/kg
Volume of distribution 2.02 L/kg
Tmax 2 hours
Estimated absorption half-life 2.2 hours
LD50 3360 mg/kg
NOAEL 50 mg/kg
Doses of 50 mg can delay fatigue
Doses of 250 mg have an effect that last 4 hours
Increases Serotonin 30% above baseline
I.G. administration
Salidroside tmax = 0.3±0.1
Salidroside clearance rate = 2.54±0.15 L/h
Salidroside volume of distribution 4.46±1.19 L/kg
Salidroside bioavailability 51.97±2.67%
I.V. administration
Salidroside volume of distribution 0.98±0.33 L/kg
Salidroside clearance rate 1.78±0.36 L/h
Salidroside half-life 0.7±0.21 hours
Salidroside half-life 0.38 hours (0.693*vd/cl)