Half-life 2.19 hours
Clearance rate: 0.037 L/kg/hr
Volume of distribution: 0.117 L/kg
Tmax: 1.25 hours
Absorption half-life: 25 minutes
LD50: 1,200 mg/kg
NOAEL: 16 mg/kg/day (52-week study)
LOEL: 1 mg/kg
NOEL: 0.33 mg/kg
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5221548/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5221548/table/t1-dddt-11-135/?report=objectonly
Vd and Cl were calculated by dividing the results by the avg mass of subjects.
No comments:
Post a Comment
Note: Only a member of this blog may post a comment.