Ibuprofen

Half-life 2.19 hours
Clearance rate: 0.037 L/kg/hr
Volume of distribution: 0.117 L/kg
Tmax: 1.25 hours
Absorption half-life: 25 minutes

LD50: 1,200 mg/kg

NOAEL: 16 mg/kg/day (52-week study)

LOEL: 1 mg/kg

NOEL: 0.33 mg/kg

https://www.mattilsynet.no/kosmetikk/stoffer_i_kosmetikk/risk_profile_ibuprofen.9874/binary/Risk%20Profile%20Ibuprofen

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5221548/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5221548/table/t1-dddt-11-135/?report=objectonly


Vd and Cl were calculated by dividing the results by the avg mass of subjects.

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